Early-onset neonatal infection occurs within the first 72 hours of life, and is typically caused by GBS. About 90% of cases with GBS present within 24 hours of birth.
Symptoms of early-onset GBS infection may be non-specific, including temperature instability, poor feeding, excessive crying and respiratory distress. It typically presents with sepsis (69%), pneumonia (26%), respiratory distress (13%), and meningitis (11%).
NICE: antibiotics for early-onset neonatal infection guideline – National Institute for Health and Care Excellence (2010). Antibiotics for early-onset neonatal infection . CG149. London: NICE.