Tip 130: ranitidine in preterm infants

There is a strong statistical evidence to suggest that ranitidine increases the risk of both NEC and infection in preterm infants, but none of the data so far comes from an RCT.

References:

Chandrasekaran M., Fleming P. (2014). Question 1: does the use of ranitidine increase the risk of NEC in preterm infants? Arch Dis Child; 99(4): 390-2.

Cotten C.M., Malcolm W.F., 2013. Ranitidine use is associated with increased morbidity and mortality in very low birthweight infants. Evid Based Med; 18(1): 36-7. 

 

 

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