Tip 130: ranitidine in preterm infants

There is a strong statistical evidence to suggest that ranitidine increases the risk of both NEC and infection in preterm infants, but none of the data so far comes from an RCT.


Chandrasekaran M., Fleming P. (2014). Question 1: does the use of ranitidine increase the risk of NEC in preterm infants? Arch Dis Child; 99(4): 390-2.

Cotten C.M., Malcolm W.F., 2013. Ranitidine use is associated with increased morbidity and mortality in very low birthweight infants. Evid Based Med; 18(1): 36-7. 



This entry was posted in Gastrointestinal, Infection, Prematurity. Bookmark the permalink.

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