Tip 68: postnatal diuresis

At birth, body weight in water is ~75% at term and ~80–85% at 26-31/40. 

An abrupt reduction of the interstitial fluid occurs shortly after birth, usually on day 2-3, triggered by atrial natriuretic peptide. This is delayed in babies with respiratory distress syndrome.

Reference: Modi, N. ‘Clinical implications of postnatal alteration in body water distribution.’ Seminars in Neonatology. 2003: 8; 301-306.

First published: 18/03/14

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