Tip 76: PDA 2

Due to an increased left (aorta) to right (pulmonary artery) shunting, a significant PDA can cause renal impairment / failure, intestinal perforation / NEC, and severe IVH / PVL possibly due to systemic ‘steal’.

The increase pulmonary blood flow can lead to alveolar pulmonary oedema, decreased lung compliance, difficulty weaning off mechanical ventilation and subsequently chronic lung disease.

Reference:  Hamrick S., Hansmann G., 2010. Patent Ductus Arteriosus of the Preterm Infant. Pediatrics; 125 (5): 1020 – 1030.

First published: 28/03/14

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