The more common causes of acute liver failure (ALF) in a neonatal intensive care unit are from ischaemic injury (at birth or after cardiac arrest) and congestive cardiac failure. If the cause is rectified, the liver usually recovers. Other causes of ALF include:
- inborn errors of metabolism (e.g. galactosaemia)
- perinatal infections (e.g. hepatitis B, parvovirus)
- haematological malignancies.