Tip 142: dopamine

Dopamine is a naturally occurring catecholamine precursor of noradrenaline.

Dopamine affects all three major determinants of cardiovascular function (preload, myocardial contractility and afterload). It increases myocardial contractility, heart rate and systemic vascular resistance by stimulation of the alpha and beta receptors. It also exerts renal and endocrine effects which are dose-dependant.

Reference:  Patwardhan, K. (2009). Inotropes in term neonates. Infant5(1), 12.

First published: 15/07/14

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