Tip 22: congenital diaphragmatic hernia (correction)

Congenital diaphragmatic hernia (CDH) occurs in 1 in 3000 – 4000 live births. Nearly 70% are diagnosed antenatally and about 30% of total cases die antenatally as a result of miscarriage or termination.

85% of congenital diaphragmatic hernia (CDH) is left-sided.

Postnatal morbidity is mainly due to pulmonary hypoplasia (depending on the amount of abdominal contents in the thorax) and persistent pulmonary hypertension of the newborn (PPHN). Postnatal survival ranges from 50 to 95%, thought to be mainly influenced by the size of the defect.

References: Field D, Hyman-Taylor P, Bacon C and Draper ES on behalf of MBRRACE-UK. Perinatal Confidential Enquiry – Congenital Diaphragmatic Hernia. Leicester: The Infant Mortality and Morbidity Group, Department of Health Sciences, University of Leicester. 2014.

Congenital Diaphragmatic Hernia Study Group. (2007). Defect size determines survival in infants with congenital diaphragmatic hernia. Pediatrics120(3), e651-e657.

First published 26/10/13. Updated 09/07/15.

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