Tip 33a: congenital cytomegalovirus (CMV)

In the UK, 50% women in antenatal clinics are seropositive for CMV.

Incidence of congenital CMV infection is ~3 in 1,000 live births. Placental transmission rates are ~40% during primary infection and 1% for reactivated infection.

The earlier the gestation at transmission, the worse the prognosis.

Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill.

Previously published: 08/11/13, 12/08/14, 22/07/15

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