Tip 76: PDA 2

Due to an increased left (aorta) to right (pulmonary artery) shunting, a significant PDA is associated with renal impairment / failure, intestinal perforation / NEC, and severe IVH / PVL, possibly due to systemic ‘steal’.

The increase pulmonary blood flow can lead to alveolar pulmonary oedema, decreased lung compliance, difficulty weaning off mechanical ventilation and subsequently chronic lung disease.

Reference:  Hamrick S., Hansmann G., 2010. Patent Ductus Arteriosus of the Preterm Infant. Pediatrics; 125 (5): 1020 – 1030.

Previously published: 28/03/14, 13/11/14, 20/02/15

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