Tip 83: varicella zoster immunoglobulin (VZIG)

VZIG is recommended for infants whose mothers develop chickenpox (but not shingles) in the period seven days before to seven days after delivery.

VZIG is also recommended for VZ antibody-negative infants exposed to chickenpox or shingles in the first seven days of life (other than in the mother) or while still on NNU. Most infants <28/40 will be antibody-negative.

Reference: Chapter 34, Immunisation against infectious disease (The Green Book) Public Health England, August 2015.

Previously published: 08/04/14, 11/03/15

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