Tip 145: NEC risk factors

The aetiology of NEC is multifactorial. The most important risk factors include:

  • Prematurity – median gestation of 29/40
  • Low birth weight, especially <1500g (found in 65% of cases in one study)
  • In-utero growth restriction (IUGR), especially with absent / reversed end-diastolic flow in the fetal umbilical artery
  • Patent ductus arteriosus (PDA)
  • Formula milk feeds

Reference: Fox T.P., Godavitarne C., (2012). What Really Causes Necrotising Enterocolitis? ISRN Gastroenterology, article ID 628317

Previously published: 22/07/14, 06/07/15

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