Tip 159: pulse oximetry screening

PulseOx is a large multicentre UK study of pulse oximetry screening (~20,000 neonates >35/40).

53 had major congenital heart disease (24 critical), a prevalence of 2·6/1000 live births. 35 were suspected from antenatal ultrasound scan. After excluding these, the sensitivity of pulse oximetry to detect congenital heart disease was 58% (28 – 85) for critical cases and 29% (15 – 46) for all cases.

Reference: Ewer, A. K., Middleton, L. J., Furmston, A. T., Bhoyar, A., Daniels, J. P., Thangaratinam, S., … & Khan, K. S. (2011). Pulse oximetry screening for congenital heart defects in newborn infants (PulseOx): a test accuracy study. The Lancet, 378(9793), 785-794.

Previously published: 28/08/14

This entry was posted in Cardiac, Congenital anomalies, Screening, Trials. Bookmark the permalink.

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