Tip 234: chorioamnionitis

Chorioamnionitis is infection of the amniotic fluid, membranes, placenta, and/or decidua.

It is a major risk factor for neonatal sepsis.

Diagnosis is sometimes made by the presence of maternal fever alone, but for research purposes is defined by the presence of maternal fever >38oC and >1 of the following:

  • maternal leukocytosis (>15)
  • maternal tachycardia (>100bpm)
  • uterine tenderness
  • fetal tachycardia (>160bpm)
  • foul odour of amniotic fluid

Reference: Polin, R. A., Papile, L. A., Baley, J. E., Bhutani, V. K., Carlo, W. A., Cummings, J., … & Watterberg, K. L. (2012). Management of neonates with suspected or proven early-onset bacterial sepsis. Pediatrics, 129(5), 1006-1015.

Previously published: 31/03/15

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