Tip 15: hypothermia in preterm infants

Why are we so careful to keep preterm babies warm?

The first Epicure study revealed that an admission temperature <35ºC was independently associated with the risk of death. Morbidity is also worsened, especially respiratory distress syndrome and chronic lung disease.

A study in 2007 showed that admission temperature was inversely related to mortality (28% increase per 1ºC decrease) and late-onset sepsis (11% increase per 1ºC decrease).

References: Costeloe K et al. The Epicure study: Outcomes to discharge from hospital for infants born at the threshold of viability. Pediatrics 2000;106:659-671.

Laptook AR, Salhab W, Bhaskar B. Admission temperature of low birth weight infants: predictors and associated morbidities. Pediatrics. 2007;119(3):e643-9.

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