Category Archives: Gastrointestinal

Tip 20: ADEPT

ADEPT is the Abnormal Doppler Enteral Prescription Trial (2012, 404 babies). The main finding was that there was no benefit to delayed initiation of feeds (5 – 6 days of age) vs. early initiation of feeds (24 – 48h age) in … Continue reading

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Tip 238: meconium plug syndrome

A meconium plug causing intestinal obstruction is usually benign and clears after rectal stimulation or contrast enema.  If regular bowel movement does not occur afterwards, a rectal biopsy is recommended to look for Hirschprung’s disease. Meconium plug syndrome is not the … Continue reading

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Tip 213: anorectal malformations 2

Anorectal malformations can be associated with other congenital anomalies such as : CHARGE (Coloboma, Heart defects, Atresia of the nasal choanae, Retardation of growth, Genital or urinary abnormalities, Ear abnormalities) VACTERL (Vertebral anomalies, Anal atresia, Cardiac defects, Tracheo-Esophageal fistula, Renal anomalies, Limb defects). Reference: Levitt, M. A., & Peña, A. (2007). Anorectal … Continue reading

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Tip 212: anorectal malformations

These are a wide spectrum of disorders affecting 1 in 5000 live births. The more proximal the lesion, the more complex the surgical input required. Reference: Levitt, M. A., & Peña, A. (2007). Anorectal malformations. Orphanet J Rare Dis, 2(33), 1-13. Previously published: … Continue reading

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Tip 208: duodenal atresia 2

Duodenal atresia occurs in 1 per 5,000 – 10,000 live births, involving male infants more commonly than female infants. Down syndrome occurs in ~25%; congenital heart disease occurs in ~20%. Reference: Kimura, K. (2000). Bilious Vomiting in the Newborn: Rapid Diagnosis … Continue reading

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Tip 207: Hirshprung’s disease

Hirschsprung’s disease is caused by the failed migration of colonic ganglion cells during gestation. Varying lengths of the distal colon are unable to relax, causing functional colonic obstruction. It most commonly involves the rectosigmoid region of the colon but can affect … Continue reading

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Tip 206: duodenal atresia

Duodenal atresia is a congenital obstruction of the second part of the duodenum caused by a failure of recanalization during the early gestational stage. The pregnancy is associated with polyhydramnios, as it is in many cases where the infant is subsequently … Continue reading

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