Category Archives: Haematology

Tip 119: neutropenia

Bacterial infection may induce a transient neutropenia, especially in preterm infants. If it persists >12 hours in the presence of clinical sepsis, it is a poor prognostic sign. Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill. Advertisements

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Tip 110: polycythaemia 2

Risk factors for polycythaemia include: IUGR Infant of diabetic mother Twin-to-twin transfusion recipient Delayed cord clamping Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill.

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Tip 107: polycythaemia

Polycythaemia (a venous haematocrit above 0.65) is relatively common. Most babies are asymptomatic, though a small proportion of babies develop clinical signs related to hyperviscosity, which include: Plethora Jaundice Lethargy Poor suck and feeding Irritability Tachypnoea and tachycardia Hypoglycaemia A … Continue reading

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Tip 103: normal coagulation

Values for coagulation parameters are dependant on the gestational and postnatal age. In both preterm and term infants, most haemostatic parameters are at adult values at 6 months of age (i.e. preterm infants have accelerated maturation). Reference: Guideline for the investigation … Continue reading

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Tip 101: vitamin K deficiency bleeding

Also known as haemorrhagic disease of the newborn, vitamin K deficiency bleeding is defined as a bleeding disorder in which the coagulation is rapidly corrected by vitamin K supplementation and is suggested by an INR of 4 with a normal … Continue reading

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Tip 65: irradiation of blood products for the neonate

The following blood products should be irradiated (<24h) prior to transfusion: in-utero red cells or platelets red cells following in-utero red cell or platelet transfusion, until 6/12 CGA platelets following in-utero platelet transfusion, until 6/12 CGA donor is a 1st … Continue reading

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Tip 37: the PINT study

This study compared low and high haemoglobin thresholds for packed red blood cell (RBC) transfusion in premature infants <1000g. Thresholds were decided by days of age, type of sample and the presence or absence of respiratory support. The high thresholds … Continue reading

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