Category Archives: Prematurity

Tip 34a: thrombocytopenia (preterm)

Early-onset thrombocytopenia (<72h, plts <150 x 109/L) in preterm infants is most likely due to placental insufficiency, perinatal asphyxia, perinatal or congenital infection, and should resolve within 14 days. Reference: Chakravorty, S. and Roberts, I., 2012. How I manage neonatal … Continue reading

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Tip 32: specialist preterm milks 2

Nutriprem 2 and SMA Gold Prem 2 contains slightly less Kcal, protein, Ca, PO4 & iron than Nutriprem 1 and SMA Gold Prem 1. Babies on this milk still require vitamin supplementation but not iron. It is generally introduced to … Continue reading

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Tip 28: NEC stages

The modified Bell’s stages for NEC are: 1 (suspected) – general features of sepsis, mild abdo distension, increased NG asp, AXR: normal/mild ileus. 2a (confirmed) – prominent abdo distension, bloody stools, mild abdo tenderness, AXR: thickened bowel wall, focal pneumatosis. … Continue reading

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Tip 23: developmental follow-up for preterm infants

Enhanced developmental support and surveillance by a multidisciplinary team should be provided up to 2 years (corrected age) for children born preterm who: have a developmental problem, or are born <30/40, or are born 30 – 36/40 and have at … Continue reading

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Tip 251: cerebral palsy in preterm infants

Cerebral palsy prevalence increases with decreasing gestational age at birth. The following are independent risk factors for cerebral palsy in preterm infants: grade 3 or 4 intraventricular haemorrhage cystic periventricular leukomalacia neonatal sepsis bronchopulmonary dysplasia for which mechanical ventilation was … Continue reading

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Tip 20: ADEPT

ADEPT is the Abnormal Doppler Enteral Prescription Trial (2012, 404 babies). The main finding was that there was no benefit to delayed initiation of feeds (5 – 6 days of age) vs. early initiation of feeds (24 – 48h age) in … Continue reading

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Tip 17b: antenatal steroids

Treatment with antenatal corticosteroids in preterm babies is associated with an overall reduction in: perinatal death (RR 0.72, 95% CI 0.58 to 0.89) neonatal death (RR 0.69, 95% CI 0.59 to 0.81) RDS (RR 0.66, 95% CI 0.56 to 0.77) intraventricular haemorrhage (RR … Continue reading

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