Category Archives: Prematurity

Tip 2: ROP screening

100% neonates <32/40 or <1501g at birth need to be screened for retinopathy of prematurity (ROP). <27/40, the first screening should be at 30-31/40 CGA. For all other eligible babies, the first screening should be at 4-5/52 age, before discharge from … Continue reading

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Tip 248: osteopenia of prematurity 2

The following all increase the risk of fractures in association with osteopenia (or metabolic bone disease) of prematurity: NEC Taking >30 days to establish full enteral nutrition Conjugated hyperbilirubinaemia Chronic lung disease Receiving chronic furosemide The most common period for fractures … Continue reading

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Tip 247: gestational borderline viability

The Nuffield Council on Bioethics produced a framework for clinical practice in 2006 regarding the resuscitation of premature babies <26/40. <22/40 =  any intervention must be within an approved research study. 22 – 22+6/40 = standard practice NOT to resuscitate. … Continue reading

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Tip 214: EPICure survival statistics of extreme prematurity

EPICure is a population-based study of extremely premature infants, looking at their survival and later health challenges. It was initially undertaken in 1995 (EPICure 1) and repeated in 2006 (EPICure 2). The 2006 data is commonly used, alongside unit’s own … Continue reading

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Tip 211: retinopathy of prematurity (ROP)

ROP is classified (internationally agreed) by: Zone of involvement (centred around the optic disc) Stage of appearance Presence of ‘plus’ disease – abnormalities of posterior retinal or iris blood vessels Evidence of ROP in zone 1 (around the optic disc), … Continue reading

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Tip 197: iron 2

Without an exogenous source of iron, the preterm infant becomes depleted by about eight weeks. External link: Larmour, K., Shaw, V., 2016. Enteral nutrition for the preterm infant, version 2.0. Great Ormond Street Hospital for Children NHS Trust: London. Previously published: … Continue reading

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Tip 193: PDA 3

The clinical features of a patent ductus arteriosus include: Bounding pulses Active precordium (presence of ventricular heave) Continuous / systolic murmur in pulmonary area (left infraclavicular) Respiratory distress failing to improve or deteriorating at 5 – 10 days of life, including apnoea … Continue reading

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