Category Archives: Prematurity

Tip 20: ADEPT

ADEPT is the Abnormal Doppler Enteral Prescription Trial (2012, 404 babies). The main finding was that there was no benefit to delayed initiation of feeds (5 – 6 days of age) vs. early initiation of feeds (24 – 48h age) in … Continue reading

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Tip 17b: antenatal steroids

Treatment with antenatal corticosteroids in preterm babies is associated with an overall reduction in: perinatal death (RR 0.72, 95% CI 0.58 to 0.89) neonatal death (RR 0.69, 95% CI 0.59 to 0.81) RDS (RR 0.66, 95% CI 0.56 to 0.77) intraventricular haemorrhage (RR … Continue reading

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Tip 17a: antenatal steroids

Antenatal steroids are recommended for women in suspected or established preterm labour, are having a planned preterm birth or have premature prolonged rupture of membranes (P‑PROM) in order to reduce morbidity in the baby. To be definitely offered between 26+0 and 33+6 … Continue reading

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Tip 16: metabolic bone disease of prematurity

Premature babies are at risk of osteopenia due to lack of minerals normally accumulated in the last trimester. This increases the risk of fractures in the short-term and short stature in the long-term. All enterally fed very preterm babies should … Continue reading

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Tip 15: hypothermia in preterm infants

Why are we so careful to keep preterm babies warm? The first Epicure study revealed that an admission temperature <35ºC was independently associated with the risk of death. Morbidity is also worsened, especially respiratory distress syndrome and chronic lung disease. A study in … Continue reading

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Tip 4: neutropenia

Neutropenia is often defined as <1.1 x 109/L. The incidence increases with decreasing birth weight, seen in 3% term infants weighing >2500g and up to 38% of those weighing <1000g. Reference: Nittala, S., Subbarao, G. C., & Maheshwari, A. (2012). Evaluation … Continue reading

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Tip 2: ROP screening

100% neonates <32/40 or <1501g at birth need to be screened for retinopathy of prematurity (ROP). <27/40, the first screening should be at 30-31/40 CGA. For all other eligible babies, the first screening should be at 4-5/52 age, before discharge from … Continue reading

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