Category Archives: Prematurity

Tip 172: the CAP trial

The Caffeine for Apnoea of Prematurity (CAP) trial enrolled 2006 infants, birth weights 500 – 1250 grams, to receive either caffeine or placebo, during the first 10 days of life. In the caffeine group, there was a decreased number requiring … Continue reading

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Tip 171: kangaroo care

In infants, kangaroo care produces increased sleep time, decreased purposeless motor activity, decreased crying, improved weight gain, increased alertness and decreased length of stay. Emotional benefits for parents include enhanced parent-infant bonding, lower rates of depression, and greater confidence in … Continue reading

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Tip 169: developmental care 2

Developmental care aims to improve neurodevelopmental outcomes in neonates. In animal studies, experiences of pain during the neonatal period have been linked with long lasting accentuated stress responses, altered neural circuits, learning deficits, and behavioural changes. Reference:  Sizun, et al … Continue reading

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Tip 167: pulmonary haemorrhage 2

Treatment of pulmonary haemorrhage comprises: high PEEP on ventilator (redistribute the fluid back into the interstitial space) surfactant fluid restriction & diuretics treatment of associated problems, such as hypotension, coagulopathy & sepsis Reference: Chapter 27 – Pulmonary disease of the newborn pages … Continue reading

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Tip 166: pulmonary haemorrhage

Pulmonary haemorrhage occurs most commonly in babies <1500g, especially those with a PDA. Clinical features usually include a marked sudden deterioration in ventilation, coupled with hypotension. Reference: Chapter 27 – Pulmonary disease of the newborn pages 509 – 511, in Rennie … Continue reading

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Tip 161: the COIN trial

This is now a historical trial but is important to know about. COIN is CPAP Or INtubation at birth for babies born at 25+0 – 28+6 weeks’ gestation. There was no significant difference in the combined outcome of death or BPD at 36/40. In … Continue reading

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Tip 156: developmental care

Developmental care relates to a broad category of interventions designed to minimise the stress of neonatal intensive care on the preterm infant’s development. Individual approaches, such as kangaroo care, as well as combination approaches, are effective in reducing length of … Continue reading

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