Category Archives: Respiratory

Tip 230: laryngomalacia 2

Laryngomalacia is associated with gastro-oesophageal reflux. It is twice as common in boys. Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill. Previously published: 12/03/15

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Tip 229: laryngomalacia

Laryngomalacia is the most common cause of infant stridor. Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill. Previously published: 10/03/15

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Tip 184: permissive hypercapnia

By tolerating higher pCO2 levels in the first few weeks of life for preterm infants, there is a reduction in the time on mechanical ventilation and its associated volutrauma and barotrauma. The long terms effects are still unknown. Widely accepted protocols … Continue reading

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Tip 181: surfactant for RDS

Prophylactic surfactant (100mg/kg) in the delivery room should be considered in: Babies born <26/40 Babies born <31/40 who require intubation in the delivery room Early rescue surfactant (200mg/kg) should be considered for premature babies if there are worsening features of RDS: Increasing oxygen requirement (>30% if … Continue reading

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Tip 178: early corticosteroids for CLD

The use of early (< 8 days) corticosteroids reduced death or CLD at 28 days (RR 0.92 [0.88-0.96]) and at 36 weeks (RR 0.89 [0.84-0.95]). Other short-term benefits were successful extubation and closure of PDA. Statistically significant short-term negative effects were: hyperglycaemia, … Continue reading

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Tip 172: the CAP trial

The Caffeine for Apnoea of Prematurity (CAP) trial enrolled 2006 infants, birth weights 500 – 1250 grams, to receive either caffeine or placebo, during the first 10 days of life. In the caffeine group, there was a decreased number requiring … Continue reading

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Tip 167: pulmonary haemorrhage 2

Treatment of pulmonary haemorrhage comprises: high PEEP on ventilator (redistribute the fluid back into the interstitial space) surfactant fluid restriction & diuretics treatment of associated problems, such as hypotension, coagulopathy & sepsis Reference: Chapter 27 – Pulmonary disease of the newborn pages … Continue reading

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