Category Archives: Antenatal

Tip 21b: maternal diabetes

The rates of all of the following are significantly higher in women with diabetes or their babies compared to matched controls: Preterm birth (31% vs. 10%) Macrosomia (41% vs. 16%) Hypoglycaemia (14% vs. 1%) Jaundice (46% vs. 23%) Respiratory distress (12% vs. 1%). … Continue reading

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Tip 21a: maternal diabetes

~5% of all pregnancies involve women with diabetes. Nearly 90% of these are due to gestational diabetes. Reference: National Institute for Health and Care Excellence (2015).  Diabetes in pregnancy: management of diabetes and its complications from preconception to the postnatal period. … Continue reading

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Tip 19b: congenital rubella syndrome

In the presence of maternal infection, transmission is ~50% in the first month of pregnancy, reducing to 10% in the third month of pregnancy. Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill.

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Tip 19a: congenital rubella syndrome

The classical trial of congenital rubella syndrome consists of: cataracts, deafness and congenital heart defects (especially pulmonary stenosis). Other features include: microcephaly, developmental delay, jaundice, thrombocytopenia and osteitis. Reference: Rennie & Roberton’s Textbook of Neonatology, 5th Ed, 2005. London: Churchill.

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Tip 17b: antenatal steroids

Treatment with antenatal corticosteroids in preterm babies is associated with an overall reduction in: perinatal death (RR 0.72, 95% CI 0.58 to 0.89) neonatal death (RR 0.69, 95% CI 0.59 to 0.81) RDS (RR 0.66, 95% CI 0.56 to 0.77) intraventricular haemorrhage (RR … Continue reading

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Tip 17a: antenatal steroids

Antenatal steroids are recommended for women in suspected or established preterm labour, are having a planned preterm birth or have premature prolonged rupture of membranes (P‑PROM) in order to reduce morbidity in the baby. To be definitely offered between 26+0 and 33+6 … Continue reading

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Tip 9: twin-to-twin transfusion syndrome (TTTS)

>25% weight discordance between twins in-utero is an important clinical indicator for TTTS. Monochorionic (MC) pregnancies are monitored fortnightly from the second trimester (>16/40). Incidence of TTTS in MC twins is 15%. Reference: NICE. Multiple pregnancy: antenatal care for twin and … Continue reading

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